Hyaluronic Acid

Physiological role and functionalities

Hyaluronic Acid as a component of the human body

Hyaluronic Acid, also known as Hyaluronan, is a natural component of most connective tissues, such as synovial fluid and the vitreous humor of the eye. It is involved in tissue hydration and structural scaffolding and provides viscoelasticity, which results in lubrication and shock absorbing functionalities.

Hyaluronic Acid is also involved in more advanced functions. With its ability to bind to multiple extracellular proteins distributed among numerous pathophysiological systems, it contributes to the modulation of many biochemical processes such as cell proliferation and differentiation, cell adhesion and inflammation, wound healing and tissue repair.

Hyaluronic Acid as a component of medical products

With its renowned natural functions, combined with the fact that it is biocompatible, non-immunogenic, biodegradable and able to be further functionalized by chemical modification, Hyaluronic Acid is a key ingredient for many different types of biomaterials, medical devices and pharmaceutical products today, including injectables, colitis, hydrogel or topical medication.

Most prevalent functional uses of today are:

  • Filling, bulking in aesthetics, dermatology and urology
  • Tissue protection in cataract surgery
  • Visco-supplementation in rheumatology
  • in dermatology and ophthalmology
  • Medical device coating in surgery

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Additionally, Hyaluronic Acid is increasingly investigated and used in advanced applications such as:

  • Anti-inflammatory, wound healing in dermatology, rheumatology, dental surgery
  • Drug carrier in oncology
  • Scaffold for tissue engineering in regenerative medicine and medical research
  • Shield for surgical sites and wound healing promoter in implantology

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